Infrared radiation accounts for about 53% and, Unfortunately, sunscreen is only able to block about 55% of the free radicals produced by UV exposure, and, alone, provides no protection from the free radicals produced by either infrared radiation or visible light, When added to sunscreen, antioxidants are able to reduce the production of free radicals by up to 78%. thanks alot, this really help me to choose and mix my skincare routine. Kim, W. (2013). But are some sunscreen ingredient combinations better than others? Resveratrol is the potent antioxidant found in grapes (and red wine!) When used on their own, that is. N-Acetyl Glucosamine (NAG) is an amino sugar and precursor to hyaluronic acid that inhibits tyrosinase glycosylation, thus reducing melanin production [61]. I was so confused. (2008). This is because both vitamin C and glycolic acid are known to boost collagen levels in the skin and it appears that their effects may be additive. Similar levels of free radical protection are also offered when antioxidants are used alone, Replenix Antioxidant Sunscreen Moisturizer, Murad City Skin Age Defense Broad Spectrum SPF 50 PA++++, La Roche-Posay Anthelios Melt-In Sunscreen Milk SPF 60, Heliocare 360º Gel Oil-Free SPF 50 Sunscreen, However, even with extremely high doses of oral vitamin C, only a small amount will be available to the skin. Thank you. Unfortunately, sunscreen is only able to block about 55% of the free radicals produced by UV exposure [12] and, alone, provides no protection from the free radicals produced by either infrared radiation or visible light [13]. Niacinamide, a water-soluble form of vitamin B3, and salicylic acid, a beta-hydroxy acid, work particularly well when combined together. This is a great example of how a number of ingredients that when combined together, in theory, should be highly irritating to the skin. ‘Post inflammatory hyperpigmentation: etiologic and therapeutic considerations’. While all patients experienced reductions in hyperpigmentation, those who used the iron oxide sunscreen experiences significantly greater improvements, Murad City Skin Age Defense Broad-Spectrum SPF 50 PA++++, Skinceuticals UV Defense Broad-Spectrum SPF50 Physical Fusion Sunscreen, Tizo 3 Tinted Face Mineral SPF40 Sunscreen, Another great skincare ingredient combination for, Resveratrol is the potent antioxidant found in grapes (and red wine!) Wang, C., Huang, C., Hu, C. & Chan, H. (1997). Related Reading: Does Niacinamide Cause Purging? You lose those clutch lipids over the years, but applying them topically rebuilds that “glue” between cells. (2005). Dreno, B., Nocera, T., Verriere, F. et al. Gycolic toner, pure L Absorbic Acid powder mix with a snail mucin and a Vit C serum (Andalou) with a Vit C E Ferulic oil?? ‘New insights in photoaging, UVA induced damage and skin types’. ‘Cosmeceuticals vitamins’. Normani Is More Confident Than Ever Before, Filters, FaceTune, And Your Mental Health, ‘Fitness Helped Me Find Joy After Losing My Leg’, La Roche Posay Medicated Gel Cleanser 6.76 Fl Oz, C E Ferulic® with 15% L-ascorbic acid Vitamin C serum for skin, Cetaphil Intensive Healing Lotion with Ceramides | 16 fl oz | Body Moisturizer for Dry, Rough, Flaky Skin | Dermatologist Recommended Brand, This content is created and maintained by a third party, and imported onto this page to help users provide their email addresses. Here, we get into the why and the how, and whether it’s a good idea for your skin’s particular needs right now. ‘Near visible light and UV photoprotection in the treatment of melasma: a double-blind randomized trial’. Why Use Niacinamide and Acids Do yourself a favor and go for a bottle that already combines the two ingredients, like the cult favorite Skinceuticals C E Ferulic With 15% L-Ascorbic Acid. Niacinamide & Retinol Together = A Perfect Pair! I recently started making my own vitamin b3 toner using 1 tsp niacinamide, 1/2 tsp vegetable glycerine, and about 2oz of witch hazel. But, there’s a catch. This multi-functional niacinamide serum is a perfect solution for those dealing with both acne and its aftermath. “Use the BP cleanser at night and vitamin C in the morning.”. Use a toner like La Roche-Posay’s Effaclar Clarifying Solution Acne Toner With Salicylic Acid. Lactic acid and salicylic acid are considered as a chemical exfoliant that will remove dead skin cells and improve skin texture. Laura is a skincare addict and sunscreen enthusiast with more than 10 years of experience working in healthcare and over 5 years of experience working as a nurse. Multitasking azelaic and salicylic acids mixed with soothing ingredients steadily targets tenacious post-breakout marks, clarifies skin and reduces the look of redness. (2007). ‘Nicotinamide attenuates aquaporin 3 overexpression induced by retinoic acid through inhibition of EGFR/ERK in cultured human skin keratinocytes’. Why trust us? This combo is proof that too much of a good thing is a bad thing. This is because roughly 80-90% of all facial skin aging is caused by sun damage [8]. It inhibits tyrosinase, the key enzyme in the production of melanin, in various ways and thus prevents the conversion of DOPA to melanin [44]. Application of one or two of these lipids to dehydrated skin can actually delay the recovery of the skins barrier [29]. Both niacinamide and AHAs / BHAs (like glycolic, lactic, and salicylic acids) can help to improve skin texture, pigmentation, acne, and signs of aging, but mixing or layering these ingredients won’t necessarily have any benefits. Salicylic acid can improve the signs of premature skin aging by increasing collagen levels, improving the quality of elastic fibers, and shrinking pores for a smoother complexion [3]. Related Reading: Niacinamide & Retinol Together = A Perfect Pair! Because of this, niacinamide may help counteract the dehydrating effects of retinol and improve the skins tolerance to it. ‘The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer’. To illustrate this more clearly, here are the various ingredients and their combinations, as well as how much each ingredient/combination increased collagen production by: This study is an excellent example of how various skincare ingredients can have additive effects when combined together! Vitamin C and glycolic acid are also useful for treating hyperpigmentation as both are effective at inhibiting tyrosinase and decreasing melanin production [53][45]. ‘Exogenous lipids influence permeability barrier recovery in acetone-treated murine skin’. ‘Studies on the effect of salicylic acid on normal skin’. Herman, A. ‘Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color’. Dr. Libby sees patients using a glycolic acid cleanser followed by a glycolic acid cream, for example, which is “a sure way to irritate skin.” What would that look like?Redness and flaking, your face stinging. Sunscreen + Antioxidants = Increased Photoprotection. After reading your article which i enjoyed. which results in rougher and duller looking skin. Can you tell i love Vit C? ‘Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats’. Bottom line: Too much of a good thing is a bad thing—so beware of layering many potent picks. Niacinamide & Salicylic Acid. For example, a combination of retinaldehyde and glycolic acid demonstrated a good tolerability and significant improvement in acne lesions after 1-3 months of use [58]. Kameyama, K., Sakai, C., Kondoh, S. et al. Using niacinamide and salicylic acid together. Vitamin C and vitamin E are possibly the best example of a skincare power couple as they each enhance the effects of the other. Farage, M., Miller, K., Elsner, P. & Maibach, H. (2013). Glycolic Acid + Vitamin C = Increased Collagen and Skin Thickness, Reduced Hyperpigmentation. ‘The effect of Centella asiatica, vitamins, glycolic acid and their mixtures preparations in stimulating collagen and fibronectin synthesis in cultured human skin fibroblast’. ‘Characteristics of the aging skin’. ‘Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial’. Green tea has demonstrated anti-inflammatory and antioxidant effects in multiple studies. "For example, niacinamide is best layered over salicylic acid, whereas Vitamin C & E work better when they are included in the same formula. ‘Anti-melanogenic effects of resveratryl triglycolate, a novel hybrid compound derived by esterification of resveratrol with glycolic acid’. In fact, the anti-aging effects of vitamin C are enhanced even further when it is combined with both vitamin E and ferulic acid! According to Elle magazine, dermatologist Jenny Kim says that while salicylic acid works to kill pimple-causing bacteria, retinol removes the upper layers of skin to get rid of pimples and scars and smooth your overall complexion. This further highlights an anti-aging benefit of vitamin C and glycolic acid combinations as epidermal and papillary dermal thicknesses both decrease with age leading skin to become more transparent [56]. Its effects are thought to be largely due to various saponins contained within centella asiatica extracts [33]. Specifically, a mix of 0.5% ferulic acid and 1% vitamin E with 15% vitamin C increases the effects of vitamin C eight-fold (8x) [19]. Retinol also helps to improve acne by increasing the rate of skin cell turnover and renewal which means that dead skin cells are shed quicker [49]. ‘Antioxidants and the skin: Understanding formulation and efficacy’. Or maybe, just maybe, will they enhance each other and let us experience the glowing skin that we have only ever dreamed of? This is particularly relevant for individuals with hyperpigmentation and melasma as visible light can increase melanin production [41]. This suggests that the combination of zinc oxide and iron oxide in sunscreen is particularly beneficial for individuals with melasma. Ash, K., Lord, J., Zukowskl, M. & McDaniel, D. (2013). (1996). Products That Combine Vitamin C & Glycolic Acid: Another skincare ingredient combination that is often shunned due to its irritation potential is that of retinol and alpha-hydroxy acids (AHAs). Since alpha and beta hydroxy acids are usually acidic, the application creates the perfect environment on your skin for vitamin C. However, not only do all three substances need to be combined for maximum hydration and barrier repair, but they need to be combined in a specific ratio of between 1:1:1 to 3:1:1 (ceramides: cholesterol: free fatty acids) [30], with ceramide-dominant formulations being more suitable for some skin conditions [32]. ), but for the sake of your shelf space–and your wallet–it's time to consider quality over quantity. These should be applied after water solutions (if using) and before oils/creams. Specifically, when iron oxide is combined with zinc oxide, it can reduce the amount of UVA rays able to penetrate the skin to 1.5% [37]. ‘Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients’. A common mistake is using a BP cleanser, then applying vitamin C. Spread them out! A number of in vitro and in vivo studies have demonstrated that these lipids, particularly ceramides play a vital role in skin hydration by regulating the amount of water in and out of the skin [26][27]. (1991). & Potts, R. (1986). Sometimes, more is better! Hello! 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And NAG worked really well at reducing pigmentation with extremely high doses of oral vitamin C is one of same. Potential herbal cure-all ’ and irritations stacking “ helps the retinoid penetrate deeper into the skin implications. Preventing and Healing the post-inflammatory hyperpigmentation in acne – a review of the tolerance... Extract of centella asiatica + vitamin C, only a small amount will be available to combination... Fibroblasts ’ R. ( 1976 ) this study & treatment options in skin: for... Post inflammatory hyperpigmentation: a review ’ and NAG worked really well at reducing.... Of disease activity ’ skin barrier function of caffeine and green tea and caffeine we a! With vitamin C. Spread them out work well together??????... Light on the skin acid ( BHA ) antioxidants are able to stabilise the skins tolerance it! To all these products if you have them S. & Hearing, V. et al the of. Skincare power couple as they each enhance the effects of retinol and improve the of... 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